Instructor Resources
Introductory Cell & Molecular Biology (LB145-BioCore Spring2025)
Lyman Briggs College, Michigan State University

Instructor Resources from Spring 2023 (below) also quick access to *just* pdfs of all lecture slides used in Spring 2023

WEEK 1 |      lecture 1 key, lecture 1 pdf (CF paper, C-pack p.267, Welsh Sci Am 1995) What is Cystic Fibrosis?
              |      lecture 2 key, lecture 2 pdf (Ch1.2-ICB) What is the Heritable Material (which molecules)?                            |      announcements (or email)      |      video (2015) Malcolm     


              |      lab slides (pptx) What is Cystic Fibrosis? (see "Study Area" for Animation of PCR)                                         |      lab outline (lesson plan)         |      whiteboard (photo)     

WEEK 2 |      lecture 3 key, lecture 3 pdf (Ch4.1-ICB) Let's remember, what is Evolution? (molecular & cellular levels)?     |      announcements (or email)     |      video (2015) Malcolm     
              |      lecture 4 key, lecture 4 pdf (Ch4.2-ICB) How did Life begin/evolve on Earth (can abiotic become biotic)?                                                            |      video (2015) Malcolm     


              |      lab slides (pptx) PCR & Primer Design (Basics of DNA & PCR, chalk exercise for primer design)                  |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 3 |      lecture 5 key, lecture 5 pdf (Ch4.3-ICB & 4.4) How did Life begin/evolve on Earth (fats --> membranes)?     |      announcements (or email)     |      video (2015) Malcolm     
              |      lecture 6 key, lecture 6 pdf (Ch8.1 Photosynthesis OSB) How did organelles evolve? (Lynn Margulis)


              |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                         |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 4 |      lecture 7 key, lecture 7 pdf (Ch8.2 Photosynthesis OSB) Light reactions (how does the chloroplast capture light energy)?
              |      lecture 8 key, lecture 8 pdf (Ch8.3 Photosynthesis OSB) Calvin Cycle (how does the chloroplast convert photons into sugar)?


              |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                          |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 5 |      lecture 9 key, lecture 9 pdf (Ch11.1-ICB Paraquat?!) Photosynthesis (research: catch light energy*)                                                                      |      video (2015) Malcolm
              |      lecture 10 key, lecture 10 pdf (Ch11.2-ICB Brazil?!) Photosynthesis! (research: how create sugar*)
                                                                     |      video (2015) Malcolm


              |      lab slides (pptx) How to improve upon DRAFT1 (Title, Abstract, Methods, Results/Figures)                           |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 6 |      [ exam day ]
              |      lecture 11 key, lecture 11 pdf (CF paper, C-pack p.275, Rowe NEJM 2005) Cystic Fibrosis: Mechanisms of Disease (how does a broken CFTR gene cause the disease?)


              |      lab slides (pptx) How to write DRAFT2 (TopTen TIPS, to remember when authoring paper!)                         |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 7 |      lecture 12 key, lecture 12 pdf (Ch5.1-ICB) Cystic Fibrosis: How genetic diseases arise (radiation, UV)?                                                              |      video (2015) Malcolm
              |      lecture 13 key, lecture 13 pdf (Ch4.3 Cell Structure OSB) Cystic Fibrosis: How cells work (are prokaryotic and eukaryotic cells different)?


              |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                         |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 8 |      lecture 14 key, lecture 14 pdf (Ch4.4 Cell Structure OSB) Cystic Fibrosis: How do cells make new CFTRs when healthy (DNA -> RNA -> protein)?
              |      lecture 15 key, lecture 15 pdf (Ch8.2-ICB FRAP!) Cystic Fibrosis: How membranes behave when healthy (can CFTR flip/flop easy)?
              |      video (2015) Malcolm


              |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                         |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 9 |      lecture 16 key, lecture 16 pdf (Ch5.2 Membranes OSB) Cystic Fibrosis: How do cell membranes behave when healthy (why do we need CFTRs to carry ions)?
              |      lecture 17 key, lecture 17 pdf (Ch5.3 Membranes OSB) Cystic Fibrosis: What are ion gradients (is the CFTR a carrier or channel or pump)?


              |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                         |      lab outline (lesson plan)        |      whiteboard (photo)     

WEEK 10 |      lecture 18 key, lecture 18 pdf (Ch39.1 Respiratory System OSB) Cystic Fibrosis: How do lungs work (and how does oxygen travel in blood)?
                |      [ exam day ]     


                |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                         |      lab outline (lesson plan)       |      whiteboard (photo)     

WEEK 11 |      lecture 19 key, lecture 19 pdf (Polonsky et al NEJM 2012) Diabetes: The Past 200 Years (what causes the disease, how to cure treat it?)
                |      lecture 20 key, lecture 20 pdf (Ch23.1-ICB digestion) Diabetes: When we eat, how does the pancreas work (create insulin)?
                           |      (2020) Chris videos 23.1-3, 23.3-4+T23.2, cell, 23.6-8


                |      lab slides (pptx) How to write DRAFT1 (Title, Abstract, Methods, Predicted Results/Figures)                         |      lab outline (lesson plan)       |      whiteboard (photo)     

WEEK 12 |      lecture 21 key, lecture 12 pdf (Ch1.4-ICB DNA+ELSI) Diabetes: What's the structure of DNA (DNA & RNA looks like)?                                 |      video (2015) Malcolm     
                |      lecture 22 key, lecture 22 pdf (Ch15.3, 15.5 Genes OSB) Diabetes: Transcription and Translation (how insulin DNA-> RNA-> proteins)



WEEK 13 |      lecture 23 key, lecture 23 pdf (Ch2.1-ICB the RNAs) Diabetes: Transcription and Translation (how did researchers learn)?                                |      video (2015) Malcolm
                |      lecture 24 key, lecture 24 pdf (Ch2.4-ICB the steps) Diabetes: DNA, RNA, protein sequences of insulin (how to NCBI)?



WEEK 14 |      lecture 25 key, lecture 25 pdf (Ch10.4-ICB Make ATP) Diabetes: After insulin works, food enters.. (how does food become ATP)?                    |      video (2015) Malcolm     
                |      lecture 26 key, lecture 26 pdf (Ch10.4+ELSI) Diabetes: After insulin works, food molecules... (the other respiration, ventilation)?
                     |      video (2015) Malcolm     



WEEK 15 |      lecture 27 key, lecture 27 pdf (CancerPOP) Cancer: Pop-up Journal Club (what about other diseases?)
                |      lecture 28 key, lecture 28 pdf (Gene TherapyPOP) Gene Therapy: Pop-up Journal Club (how do we cure any disease?)






Research Projects & Publications
supporting pedagogy used in course

Contact me at:  luckie@msu.edu