WEEK 1 |     
lecture 1 key, lecture 1 pdf (CF paper, C-pack p.267, Welsh Sci Am 1995) What is Cystic Fibrosis?
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lecture 2 key, lecture 2 pdf (Ch1.2-ICB) What is the Heritable Material (which molecules)?                            |     
announcements (or email)      |     
video (2015) Malcolm     
WEEK 2 |     
lecture 3 key, lecture 3 pdf (Ch4.1-ICB) Let's remember, what is Evolution? (molecular & cellular levels)?     |     
announcements (or email)     |     
video (2015) Malcolm     
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lecture 4 key, lecture 4 pdf (Ch4.2-ICB) How did Life begin/evolve on Earth (can abiotic become biotic)?                                                            |     
video (2015) Malcolm     
WEEK 3 |     
lecture 5 key, lecture 5 pdf (Ch4.3-ICB & 4.4) How did Life begin/evolve on Earth (fats --> membranes)?     |     
announcements (or email)     |     
video (2015) Malcolm     
              |     
lecture 6 key, lecture 6 pdf (Ch8.1 Photosynthesis OSB) How did organelles evolve? (Lynn Margulis)
WEEK 4 |     
lecture 7 key, lecture 7 pdf (Ch8.2 Photosynthesis OSB) Light reactions (how does the chloroplast capture light energy)?
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lecture 8 key, lecture 8 pdf (Ch8.3 Photosynthesis OSB) Calvin Cycle (how does the chloroplast convert photons into sugar)?
WEEK 5 |     
lecture 9 key, lecture 9 pdf (Ch11.1-ICB Paraquat?!) Photosynthesis (research: catch light energy*)                                                                      |     
video (2015) Malcolm
              |     
lecture 10 key, lecture 10 pdf (Ch11.2-ICB Brazil?!) Photosynthesis! (research: how create sugar*)                                                                      |     
video (2015) Malcolm
WEEK 6 |     
[ exam day ]
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lecture 11 key, lecture 11 pdf (CF paper, C-pack p.275, Rowe NEJM 2005) Cystic Fibrosis: Mechanisms of Disease (how does a broken CFTR gene cause the disease?)
WEEK 7 |     
lecture 12 key, lecture 12 pdf (Ch5.1-ICB) Cystic Fibrosis: How genetic diseases arise (radiation, UV)?                                                              |     
video (2015) Malcolm
              |     
lecture 13 key, lecture 13 pdf (Ch4.3 Cell Structure OSB) Cystic Fibrosis: How cells work (are prokaryotic and eukaryotic cells different)?
WEEK 8 |     
lecture 14 key, lecture 14 pdf (Ch4.4 Cell Structure OSB) Cystic Fibrosis: How do cells make new CFTRs when healthy (DNA -> RNA -> protein)?
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lecture 15 key, lecture 15 pdf (Ch8.2-ICB FRAP!) Cystic Fibrosis: How membranes behave when healthy (can CFTR flip/flop easy)?               |     
video (2015) Malcolm
WEEK 9 |     
lecture 16 key, lecture 16 pdf (Ch5.2 Membranes OSB) Cystic Fibrosis: How do cell membranes behave when healthy (why do we need CFTRs to carry ions)?
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lecture 17 key, lecture 17 pdf (Ch5.3 Membranes OSB) Cystic Fibrosis: What are ion gradients (is the CFTR a carrier or channel or pump)?
WEEK 10 |     
lecture 18 key, lecture 18 pdf (Ch39.1 Respiratory System OSB) Cystic Fibrosis: How do lungs work (and how does oxygen travel in blood)?
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[ exam day ]     
WEEK 11 |     
lecture 19 key, lecture 19 pdf (Polonsky et al NEJM 2012) Diabetes: The Past 200 Years (what causes the disease, how to cure treat it?)
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lecture 20 key, lecture 20 pdf (Ch23.1-ICB digestion) Diabetes: When we eat, how does the pancreas work (create insulin)?
                           |      (2020) Chris videos 23.1-3, 23.3-4+T23.2, cell, 23.6-8
WEEK 12 |     
lecture 21 key, lecture 12 pdf (Ch1.4-ICB DNA+ELSI) Diabetes: What's the structure of DNA (DNA & RNA looks like)?                                 |     
video (2015) Malcolm     
                |     
lecture 22 key, lecture 22 pdf (Ch15.3, 15.5 Genes OSB) Diabetes: Transcription and Translation (how insulin DNA-> RNA-> proteins)
WEEK 13 |     
lecture 23 key, lecture 23 pdf (Ch2.1-ICB the RNAs) Diabetes: Transcription and Translation (how did researchers learn)?                                |     
video (2015) Malcolm
                |     
lecture 24 key, lecture 24 pdf (Ch2.4-ICB the steps) Diabetes: DNA, RNA, protein sequences of insulin (how to NCBI)?
WEEK 14 |     
lecture 25 key, lecture 25 pdf (Ch10.4-ICB Make ATP) Diabetes: After insulin works, food enters.. (how does food become ATP)?                    |     
video (2015) Malcolm     
                |     
lecture 26 key, lecture 26 pdf (Ch10.4+ELSI) Diabetes: After insulin works, food molecules... (the other respiration, ventilation)?                      |     
video (2015) Malcolm     
WEEK 15 |     
lecture 27 key, lecture 27 pdf (CancerPOP) Cancer: Pop-up Journal Club (what about other diseases?)
                |     
lecture 28 key, lecture 28 pdf (Gene TherapyPOP) Gene Therapy: Pop-up Journal Club (how do we cure any disease?)